Endotoxins - Health-based recommended occupational exposure limit

At the request of the Minister of Social Affairs and Employment, the Dutch Expert Committee on Occupational Safety (DECOS), a committee of the Health Council of the Netherlands, recommends health-based occupational exposure limits for airborne substances to which people are exposed in the workplace. These recommendations serve as a basis in setting legally binding occupational exposure limits by the Minister. In this report, the Committee considers the implications of exposure to endotoxins and recommends a health-based occupational exposure limit for these substances.

This report updates an earlier Health Council report, published in 1998, which set out the Council’s initial evaluation of the health implications of exposure to endotoxins. The present report consists of a brief summary of the earlier report, plus information gleaned from literature published since 1998. The committees’ conclusions reflect the content of scientific publications that have appeared prior to January 2010.