This advisory report, entitled “Pharmacotherapeutic interventions in drug addiction”, is the third and final report that this Committee presents in reply to previously stated requests for advice by the Minister of Health, Welfare and Sport. The first advisory report, “The prescription of heroin to heroin addicts” (1995), has led to a large-scale investigation. The results of that study were published in February 2002. The second advisory report, “Testing for drugs of abuse ”, dealt with the investigation of bodily materials (mainly urine) in order to detect drug use. This advisory report, which appeared in 1998, played a role in the establishment of the Regulation on Urine Control in Penitentiaries promulgated by the Dutch Minister of Justice in June 1999.